Antacid Medication: Short & Long Term Side Effects

25 December 2019

In today’s Health Bunker article we will discuss ‘Antacid Medication’ specifically a drug called Lansoprazole. This drug is used to treat gastroesophageal reflux disease (GERD), peptic ulcer disease and general anti-acid requirements.

It is a proton pump inhibitor (PPI) and taken by mouth, it is classed as the most potent inhibitor of acid secretion available. There are different medicinal doses dependent on requirements needed to neutralize the acid. Antacid medication side effects are numerous, and we will try to cover them all as well as drug interactions. 

This article is quite personal to us, a good friend was placed on these drugs about 20 years ago. He is now more or less house bound, losing his career and life. He spends most of his time at home, signed on the long term sick.

His GPs do not believe that prescribed Lansoprazole could of caused all of his health problems. In fact, they have said on numerous occasions, it’s all in his head. They have prescribed him antidepressants which made him suicidal.

To make matters worse last year he went for some scans, they used a contrast agent called Gadolinium, a substance classed as a ‘rare earth heavy metal’, which has caused additional health issues.

So, this is his story in his own words, he’ll remain anonymous;

‘I was first prescribed Lanzoprazole around 20 years ago when I was 25. I had started having problems with severe acid reflux. The specialist said I had a problem with the top sphincter above my stomach. I was prescribed Lansoprazole. 

I was fairly fit, I went to the gym regularly and looked very healthy. Unfortunately, these tablets were stopping natural digestive functions.

After 3 years, I started getting really bad anxiety and having cognitive problems something which until this day still rules over my everyday life. Long story short I now can’t seem to get off these tablets, when I try, I get terrible rebound and can’t function at all.

I also haven’t been able to work for six years due to anxiety and depression and over the past 3 years have developed some kind of eating issue where I can’t digest any food. I have constant fibromyalgia symptoms, bloating, and insomnia.’

‘I actually have every side effect that’s written on the leaflet insert inside the packet. Yet the doctors deny that these are caused by the drug’.

Lansoprazole: Antacid Side Effects

There are many side effects of antacid medication, but the correlation between long term use leading to other issues are just coming to light. In fact, the cold turkey side effects when coming off these drugs are actually worse than the initial illness.
These figures are from the package leaflet;

Common 1 in 100 people: Headaches, feeling sick, diarrhoea or being sick, stomach pain, wind, itchy skin rashes, feeling dizzy, dry mouth or throat.

Call your doctor right away if these side effects occur;

Un-Common 1 in 1000 people: 

  • joint pain along with a red skin rash, especially in parts of your body exposed to the sun, such as your arms, cheeks and nose – these can be signs of a rare condition called subacute cutaneous lupus erythematosus. This can happen even if you’ve been taking lansoprazole for a long time.
  • Stomach pain that seems to be getting worse – this can be a sign of liver or pancreas inflammation.
  • Depression
  • Oedema, arthralgia, myalgia, fracture of the hip, wrist or spine.

Rare 1 in 10,000 people;

  • Anaemia, Insomnia, hallucinations, confusion, restlessness, vertigo, paresthesia, somnolence, tremor, visual disturbances, glossitis, candidiasis of the oesophagus, pancreatitis, taste disturbances, liver disease – hepatitis, jaundice, Petechiae, purpura, hair loss, erythema multiforme, photosensitivity, interstitial nephritis, gynecomastia, fever, hyperhidrosis, angioedema, anorexia, impotence.

Very Rare 1 in over 10,000 people;

  • Agranulocytosis, pancytopenia, colitis, stomatitis, Steven-Johnson syndrome.

The dangers of antacids

In the UK, 2.8 million people per year use some kind of antacid medications both prescription and over the counter. The BMJ published a recent study from the U.S. which said;

‘The results suggest an excess risk of death among PPI users; risk is also increased among those without gastrointestinal conditions and with prolonged duration of use. Limiting PPI use and duration to instances where it is medically indicated may be warranted’.

Health Bunker

In general antacid ingredients are really shocking, they can contain Talc, & aluminum hydroxide. Antacids can interfere and cause kidney disease, kidney stones, and heart failure.  

Antacids that contain aluminum have been shown to have many side effects. Some also contain Titanium Dioxide which is a known carcinogen. 

Talk to your doctor if you notice any symptoms. Please look at the leaflets in the box, research the ingredients and ask questions.

Eat Well. Be Well.

Dom and Nic
Health Bunker
It’s Your Life. Own it!

*Disclaimer – Please note, we are not Doctors or trained medical professionals. We are not giving medical advice. Check with your Doctor or health practitioner before trying anything.



Medicine Net
Healthline sodium bicarbonate
Science Daily magnesium carbonate, and calcium carbonate
Pharma Journal aluminum and magnesium